Retinol 2.5%
Great product and company to deal with

You can simply sign in to your account on our website, or click the link in any email sent you about your subscription, to view, change or cancel your subscription.
Subscriptions can be cancelled with a single click after your first refill.
PLEASE NOTE: cancelling your subscription is not available until after your first refill - meaning your 2nd shipment.
This is done to ensure we can continue to offer discounts to all those who wish to subscribe.
When a customer subscribes, we do not have to pay substantial marketing costs to Google or Facebook for each order. This allows us to pass these savings on to you.
But, this falls apart if people place a subscription order to receive the free shipping and discount on their first order with us, and then immediately cancel their subscription.
Therefore, to be able to continue offering significant cost savings to subscribe and save customers, we have sadly had to make it only possible to cancel a subscription any time after the customer has received their first refill (meaning the second shipment of the product they subscribed to).
For more details of our subscription cancellation policy, or how our customer account works, check out our FAQ here.
What our customers say
Great product and company to deal with
When I'm wrong I'll admit it.
I'd previously given a poor review for this cream, as I couldn't see any difference within the first couple of weeks.
As I'd still got some leftover I continued using it and I've noticed this weekend a vast improvement with lines around my eyes and the tone of my skin.
Now I just need something to fade the pigmentation I have and I'll be happy.
Following my previous review regarding the actual product, I have to say Customer Service were excellent in dealing with the issue.
I haven’t even received my order
Excellent product
E xcellent product. Have received compliments on my skin. I’m 83 so never too old to try it. Have used this company for a long time and never been disappointed
This cream has a nice texture and smooths into my skin, leaving it soft.
The product is very good , I enjoy using the product very muchI would but this product again. However do you have ay products for hair growth
Lovely cream goes on great and skin feels lovely
I have bad sun damage patches on my arms years of sunbathing with no lotions can I use Retinol 250% on my arms to reduce the dark patches
Hi, can you please tell me if this is suitable to apply to the body please?,
I love this cream ... bought it to help my Sebaceous Hyperplasia lumps o my face .... the cream absorbs really well & isn't sticky.... I have noticed my skin is softer & my wrinkles seem better ... hopefully the results will be better the longer I use the cream .... would highly recommend ....
I have used 250% Strength Retinol Cream for many years and would recommend this product for keeping fine lines and wrinkles away.
The product is good for hydrating the skin and works well with face foundations or BB creams.
The Company always provides a good service and efficient delivery times for all their products.
I never usually leave reviews but this cream is the best I’ve tried and I’ve tried many across a myriad of pricing bands. Within 2 days there was a noticeable difference. My skin has never looked so hydrated.
The 2.5 retinol cream is a very good way of applying retinol to my very sensitive skin. It is an excellent product, as is this company. I always receive products well packed and with fast delivery.
Loved the product, and the service was absolutely excellent.
Have been using for over a month now and im a 63 year old lady and maybe I should have found this product years ago its to soon to say as my wrinkles are quite deep set in the jowl area.Love the feel and quality of this product and will vary on using but may still need some fillers along the way
It's to early to tell if the product is working. It's lovely on my face and soaks in well.
Product very gentle and nice on skin.
Will be using as my main product.
Customer service and delivery brilliant.
THIS PRODUCT IS PERFECT FOR ME. THANK YOU
I myself and several of my customers swear to this - best effect over night .
My customers are spread from 30 - 70 . They all feel an amazing improvement
Especially if they stop using it
I can not recommend this product enough!! I am turning 32 and I have large pores on my cheeks, black heads on my nose that never go away and hormonal break outs on my chin area all the time. I really didn’t trust that there were any products out there that could help, but no word of a lie, one use and I noticed a difference. And after 3 days, my black heads were completely gone and don’t return! Plus my pores are gotten dramatically smaller and I haven’t had any breakouts! I have actually been complimented on how healthy and fresh my skin looks! A+++++ for this product!
It is worth noting that I use this product at night before bed and during the day I use the vitamin C serum.
The product works wonders for my complexion. More even and smoother is the name of the game
I have used Pureclinica's retinol cream for two weeks now. It's not oily and doesn't break out my skin. I have acne prone skin that easily breaks out, especially when I try new products, but that is not the case with this product.
I've used this cream for 1o days and noticed improvements in my breakouts after the first week. I break out less now and the pimples doesn't feel as bad
I like how the product softens my skin. But my skin is too sensitive for it and I think it also caused me to break out more
I have eczema prone skin but have no issues using this product
Me and my mother both use this product. I got my dry skin from her so we tend to use the same skincare products. It is pretty effective at keeping the skin moisturized throughout the day
I like not only this but also Pureclinica's hyaluronic acid. The results I'm getting from both of those products together is good.
I am 26 years old and I have large pores. It used to cause my makeup to look terrible and face washes did not help. The retinol cream has first of all helped reduce the size of my pores but also made my makeup look much better
I really like how this product feels on my skin. It absorbs quickly and afterwards my makeup looks much better
This moisturizer is truly impressive. I actually bought it because my standart one was out of stock so I wasn't really planning on using it for long. But since it improved my skin tone and helped calm a lot of the redness and stuff that would make it look uneven, I decided to keep using it
I never paid much attention to my skin until it started showing... Pureclinica's retinol cream has made my skin less dry and dull to being shiny but not oily. The new glow is really appealing in my opinion
This is a very affordable cream. I Have used it for a week so I don't know how effective it is for wrinkles and such but I can attest to the fact that it is very moisturizing
It's a bit early to tell perhaps, but I like the texture and my skin is looking lovely in the mornings after I apply it before I go to bed
I have super sensitive skin and have allergic reactions to a lot of skincare products. Not this one though. This is the best anti ageing product I have used and I would totally recommend it
I got results quicker than I expected, maybe because I apply it twice per day
Retinol Cream feels lovely on my skin. It's absorbed quickly with no greasy feelings etc. It is definitely giving my skin a younger complexion
I have used this with their hyaluronic acid serum for the past couple of weeks for my dry skin. My face isn't nearly as dry as it has been in the past, even if I skip to put the products on when I have a stressful morning.
This is probably the first moisturizer I use that ALSO helps diminish the appearance of wrinkles. Most products just moisturize and that's it but not this one
I'm trying to spot treat some sun spots with retinol cream. Although it's having some effect, I think I need to switch over to prescription retin-a to get the effect I'm looking for
Fortunately I don't have any wrinkles that bother me, but my skin was very dull. It didn't have any glow or life to it. Pureclinica's retinol cream helped bring life to my skin again
Overall I am satisfied with this product. I thought the retinol might dry out my skin but that has not happened, despite me having such sensitive skin
I have sensitive skin but using this cream has not been an issue for me whatsoever. I wish it lasted a bit longer though.
I have purchased a few products from this company and have been pleased with them all. I have noticed a huge difference in my complexion. My skin is a lot clearer
It does make my skin texture look better.
It doesn't make my skin red despite it being so sensitive. I'm happy that this cream works for me and that I can apply it several times a week without any issues
It makes my skin feel very smooth and it's more even in general. The smoothness makes my wrinkles stand out a bit less so they're not as noticeable
I apply it once per day. I have large pores along with acne prone skin and my pores are getting smaller.
I never had a lot of acne but the few that did pop up were always big and red. I started using Pureclinica's retinol cream along with their vitamin c serum and I no longer break out
| Ingredients | Per Serving | % NRV |
|---|
Since 2005, we’ve done more than produce supplements—we create products that truly deliver results.
That starts with traceable, select ingredients, sourced for their strength and efficacy. At our UK, US, and Netherland's based facilities, certified to CGMP, ISO, and BRC standards, every step is purposefully engineered for precision and control. Advanced extraction and purification methods radically improve potency while removing impurities, without introducing toxic chemicals.
We further excel through rigorous unparalleled testing. Ingredients, production stages, and finished products undergo constant checks, with third-party labs verifying finished products.
No shortcuts, no empty hype—just supplements built on science, care, and a commitment to doing things right. Upgrade to stronger supplements, get better results.
A tiny sapling goes a long way. Through our partnership with Eden Reforestation Projects, we are helping to plant trees on a massive scale.
Every bottle you purchase helps to protect vital eco-systems, help mitigate climate change, and create jobs that help provide education, health care, and food for rural communities in Mozambique, Nepal, Madagascar, and Ethiopia.
Our aim is to plant 10 million trees by 2030.
Free overnight shipping when you spend £50 or more.
Get exceptional customer service from our team of highly trained nutritionists.
Tested by 3rd party labs to ensure they contain exactly what is stated on the label.
Consistently ranked 1st on Amazon since 2011.